Implant in systemic diseases

Implants > Implants in patients with systemic diseases

The role of our teeth

Today, our teeth are of great importance in our lives, both aesthetically and functionally. Therefore, we should always aim to protect and retain our own teeth. But if we have teeth that absolutely need to be extracted, implant placement is often sensible solution.

When it comes to implants and implant success, systemic body health is very important. Furthermore, loss of teeth can lead to an unhealthy diet, and psychological problems, affecting a person’s quality of life and self-esteem.

Contraindications of implants

In implant applications, as in every medical treatment, there are certain medical conditions where the patient should avoid receiving implant treatment. These conditions, in which implant treatment should not be performed, are called contraindications. If the contraindications are determined in advance, harmful treatments can be avoided, and every effort will be made to restore natural teeth or choose the most appropriate solution.

Local and systemic diseases

Contraindications can be divided into local and systemic. The presence of systemic diseases plays an important role in the planning and implementation of implant treatment. There are certain systemic diseases that affect bone metabolism, wound healing in tissues and ultimately the success of implant treatment. In addition, systemic diseases treated with drugs or other methods have the potential to affect implants and surrounding tissues.

Cardiovascular (Heart and Vascular Origin) Diseases

In heart disease, some patients are prescribed blood thinning medication. The use of blood thinners should be followed and consultation with the treating physician should be made when necessary to discuss treatment.

Although some diseases such as hypertension, atherosclerosis, vascular stenosis, coronary artery disease and congestive heart failure cause suppression of blood flow, a decrease in oxygen density and malnutrition of tissues, it does not necessarily prevent the integration of the implant into the bone.

Patients with cardiovascular diseases can still have clinical success with dental implants. For example, it has been proved in clinical studies that patients taking calcium channel blockers such as Nifedipine (Adalat, Nidilat, etc.) used in the treatment of congestive heart failure and hypertension, can reduce bone resorption by providing direct calcium entry into the cell. Likewise, it has been proven that calcium channel blockers reduce bone resorption by up to 50%, depending on the dose. This shows the positive mechanism of action of some heart medications.

Diabetes (Diabetes Mellitus)

Implants can be applied to diabetics in many cases by following their scientific literature. In our clinic, we have cases with a history of up to 14 years and follow-up.

If you are a diabetic and want to have an implant, you can receive a thorough examination along with all your medical history from your medical doctor, to determine if an implant is appropriate for you.

Diabetes has various systemic complications such as eye, kidney, brain vessels, micro and macro vascular disorders and wound healing disorders. In the mouth, it influences the formation of dryness, decay, oral thrush and gum disease. According to the data obtained from articles that investigated the implant success in diabetic patients who had more than one implant placed, it was concluded that the rate of implant loss in diabetic patients under control was within normal limits. The results of implant treatment performed on diabetic patients under control in our clinic also support this view.

According to the data of these studies, good glycemic control is required before and after the surgical intervention to ensure the osseointegration of the implants and to prevent a delay in the healing of the soft tissue. For this, the HbA1c test is performed, which shows the average blood-glucose concentration in the last 6 to 8 weeks. The feasibility of implant application is evaluated by the results of clinical control and anamnesis.

Dental Treatment for People Using Cortisone (Corticosteroids)

As with any drug, duration and dosing are important in the use of cortisone. The decision about implant application should be made by the physician by making the patient's general anamnesis and clinical control.

Corticosteroids are drugs with strong anti-inflammatory effects that are used in the treatment of many systemic diseases. These drugs reduce inflammation and are effective in reducing swelling and associated pain. However, it also reduces protein synthesis and delays wound healing. In addition, it reduces the number of leukocytes and lowers the patient's resistance to infection. Therefore, appropriate antibiotics should be used for 3-5 days after the initial dose.

Relationship between Bone Resorption (Osteoporosis) and Teeth

In the light of the data below, it can be concluded that osteoporosis does not constitute a contraindication for dental implant treatment. However, it is still recommended to provide a complete oral examination before to determine whether a surgical procedure is appropriate.

Osteoporosis is a bone disease that occurs in the skeleton due to the thinning of the protein mesh in the bone as a result of a decrease in bone mass with age, causing the bones to break very easily. The osteoporotic (bone resorption) changes in the jaws are similar to those in other bones of the body. Because osteoporosis causes greater loss of trabecular bone density than cortical bone, it is not a contraindication for immediate stabilization of implants. In many clinical studies conducted after menopause over the age of 50, loss rates close to other patients were shown and it was stated that hormone replacement therapy (HRT) did not affect the loss rate. In the analysis of many literature studies by Chen et al., the relationship between osteoporosis and dental implant loss was not found to be statistically significant.

Bisphosphonate Use and Implant Treatments

Intravenous bisphosphonates pose a high risk for implant surgery. The duration and dosage of these drugs taken orally, as well as the other diseases and drugs used, along with a general clinical examination and anamnesis should be evaluated by the physician who will administer the treatment together with the serum CTX test when necessary.

Bisphosphonates are a group of drugs frequently used for many bone diseases and are approved by the US Food and Drug Administration (FDA) for the treatment of osteoporosis, metastatic bone tumor and Paget's disease. Bisphosphonates act by suppressing osteoclasts or reducing bone resorption.

The relationship between radiotherapy and implant treatment

Head and neck radiotherapy causes oxygen deficiency in tissues, shrinkage of vessels and tissue deterioration. The tissue cannot be reshaped due to the decrease in its vitality and the risk of bone destruction increases.

The risk of lack of implant integration increased 2-3 times in patients who received radiotherapy. It has been reported that the use of hyperbaric oxygen at a pressure above 1 ATM for 20 times before and after the procedure increases the success of people in this situation. Another issue is radiotherapy after implant application. How long after the implant is applied and the dosing of this treatment has a significant effect on the result. It has been reported that the risk is lower with implants that have been applied for a long time.

Ectodermal Dysplasia and Implant Relationship

Ectodermal dysplasia is an inherited disease that manifests itself with the disorder of tissues such as hair, skin, nails and teeth. The most common intraoral clinical manifestation is the absence of a single or mostly multiple teeth.

Classical dental treatment and prosthetic techniques often fails because there is not enough hard and soft tissue support. The correct method is implant-supported treatments to be performed after the oral development is completed. While implant application is not recommended in the treatment of single tooth deficiency, it has been determined that the anterior region of the lower jaw is the most suitable region for implant applications in severe hypodontia cases. Studies have reported significantly lower maintenance and success rates in the upper jaw than in the lower jaw.

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